Epitope Health
Not medical advice. Possible anaphylaxis: use epinephrine and call 911.Read the full note

Epitope Health teaches what published research and FDA labels say, and how strong that evidence is. It cannot know your situation, and nothing here is a diagnosis, a dose for one person, or a decision about whether a food, medicine or procedure suits one person. Those decisions belong with a licensed clinician who can examine you.

If a reaction is happening now, use epinephrine if it has been prescribed and call 911. After surgery, trouble breathing or chest pain needs 911. If you are thinking about harming yourself, call or text 988, any time.

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Home / New in the research

New in the research

Recent guidelines, trials and reviews in allergy, immune health and perioperative care, each shown with its title, journal, date and one sentence from its abstract, word for word.

15 papers, refreshed October 23, 2026

How these papers are chosen

A script searches PubMed every week for papers added in the last 90 days in leading general, allergy, pediatric, gastroenterology and anesthesia journals. It keeps only practice guidelines, consensus statements, meta-analyses, systematic reviews and randomized trials, and removes comments, letters, editorials, case reports and animal-only studies. It is the same quality rule Anthia uses for live PubMed results.

Nothing on this page is written by AI or by us about the papers. The sentence shown is copied from each abstract as published. The grade comes from the publication type PubMed records. These papers are not yet part of the verified library, and the guides do not rely on them until they are verified and added.

Allergy and immune health

Food allergy, anaphylaxis, allergic rhinitis, eczema, hives, eosinophilic esophagitis and allergen immunotherapy.

  1. NutrientsAdded to PubMed October 16, 2026E1StrongSystematic review

    Dietary Management of IgE-Mediated and Non-IgE-Mediated Food Allergies: A Systematic Review of Current Evidence and Clinical Implications.

    Current evidence supports individualized dietary management based on regular reassessment, nutritional monitoring, supervised food reintroduction when clinically appropriate, and multidisciplinary care.

    One sentence from the abstract (conclusions section), word for word. PMID 42884631.
  2. N Engl J MedAdded to PubMed September 16, 2026E1StrongRandomized trial

    Trial of a Maternal Diet Rich in Eggs and Peanuts to Reduce Infant Allergy.

    The ingestion of high amounts of egg and peanut during pregnancy and lactation did not result in a significantly lower risk of the development of egg or peanut allergy in infants by 1 year of age than ingestion of low amounts of these foods.

    One sentence from the abstract (conclusions section), word for word. PMID 42748429.
  3. LancetAdded to PubMed August 21, 2026E1StrongRandomized trial

    Rezpegaldesleukin treatment of moderate-to-severe atopic dermatitis (REZOLVE-AD): final results from the 16-week induction period of an international, double-blind, placebo-controlled, randomised phase 2b study.

    Over the 16-week induction period, rezpegaldesleukin treatment resulted in significant and clinically meaningful improvements across multiple clinical endpoints, including the primary endpoint of EASI percentage change from baseline, in comparison with placebo.

    One sentence from the abstract (interpretation section), word for word. PMID 42628554.
  4. AllergyAdded to PubMed August 2, 2026E1StrongRandomized trial

    Effect of Abrocitinib on the Skin Microbiome in Patients With Moderate-to-Severe Atopic Dermatitis.

    Abrocitinib treatment is associated with beneficial changes in the skin microbiome, notably a reduction in S. aureus and increased microbial diversity.

    One sentence from the abstract (conclusions section), word for word. PMID 42543003.
  5. Clin Exp AllergyAdded to PubMed July 30, 2026E2GoodGuideline

    Hospital-Based Food Challenges for the Diagnosis of Food Allergy-A BSACI Clinical Practice Statement.

    The decision to pause or stop a challenge should be based on international guidance and clinician judgement, but also consider an individual's symptom history and their preferences.

    One sentence from the abstract, word for word. PMID 42529903.
  6. JAMA PediatrAdded to PubMed July 27, 2026E1StrongRandomized trial

    Treatment of Multifood Allergy With Omalizumab or Multiallergen Oral Immunotherapy: A Randomized Clinical Trial.

    Although the ITT analysis found a higher rate of treatment success in those receiving omalizumab compared with MOIT, results suggest that the difference was largely driven by the high rate of study discontinuation in the participants treated with MOIT, mostly related to adverse events.

    One sentence from the abstract (conclusions and relevance section), word for word. PMID 42507431.
  7. J Allergy Clin ImmunolAdded to PubMed July 24, 2026E1StrongRandomized trial

    Epitope-specific IgE profiles are predictive of desensitization and remission in the IMPACT trial.

    Baseline epitope IgE profiles can predict remission outcome for children undergoing pnOIT.

    One sentence from the abstract (conclusions section), word for word. PMID 42498124.

Anesthesia and perioperative care

Anesthesia and sedation, preparation for surgery, perioperative medicines, and pain and recovery after surgery.

  1. Reg Anesth Pain MedAdded to PubMed September 11, 2026E1StrongRandomized trial

    Caudal versus penile block and urethrocutaneous fistula formation following hypospadias repair in children <2 years: a multicenter randomized clinical trial.

    In this early terminated randomized trial, no statistically significant difference in UCF formation was observed between caudal and penile blocks.

    One sentence from the abstract (conclusion section), word for word. PMID 42727983.
  2. AnesthesiologyAdded to PubMed September 8, 2026E1StrongMeta-analysis

    Effectiveness of Selective Cyclooxygenase-2 Inhibitors for Postoperative Pain Management Using Multidimensional Pain Assessment: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

    Perioperative selective COX‑2 inhibitors likely provide a clinically meaningful reduction in acute pain - related interference with daily function and may improve chronic pain and quality of recovery.

    One sentence from the abstract (conclusions section), word for word. PMID 42708838.
  3. Eur J AnaesthesiolAdded to PubMed September 4, 2026E1StrongMeta-analysis

    Remimazolam versus sevoflurane for general anaesthesia: A meta-analysis with trial sequential analysis of haemodynamic and clinical outcomes.

    Remimazolam was associated with a lower incidence of intraoperative hypotension compared with sevoflurane, while differences in MAP and HR were limited to specific time points.

    One sentence from the abstract (conclusions section), word for word. PMID 42693830.
  4. JAMA SurgAdded to PubMed August 19, 2026E1StrongRandomized trial

    Preoperative High-Dose Corticosteroids in Digestive Cancer Surgery: A Randomized Clinical Trial.

    A preoperative pulse dose of corticosteroids had no benefit on postoperative outcomes in elective digestive cancer surgery and should not be recommended in routine practice.

    One sentence from the abstract (conclusions and relevance section), word for word. PMID 42616512.
  5. Paediatr AnaesthAdded to PubMed August 18, 2026E1StrongMeta-analysis

    Pediatric Postoperative Acute Kidney Injury After Noncardiac Surgery: A Systematic Review and Meta-Analysis.

    The reported incidence of postoperative AKI in children undergoing noncardiac surgery remains uncertain due to substantial heterogeneity and overrepresentation of high-risk populations.

    One sentence from the abstract (conclusion section), word for word. PMID 42610771.
  6. Paediatr AnaesthAdded to PubMed August 13, 2026E1StrongRandomized trial

    EEG-Guided Sevoflurane Anesthesia and Emergence Delirium in Children: A Randomized Controlled Trial.

    EEG-guided anesthesia was associated with lower PAEDS scores and reduced sevoflurane consumption compared with standard management.

    One sentence from the abstract (conclusion section), word for word. PMID 42590887.
  7. Paediatr AnaesthAdded to PubMed August 12, 2026E1StrongMeta-analysis

    Pre-Extubation Low-Dose Propofol in Pediatric Ear, Nose, and Throat Procedures: A Meta-Analysis With Trial Sequential Analysis.

    Our findings suggest that pre-extubation propofol probably reduces the incidence of EA in pediatric ENT surgery, supported by moderate-certainty evidence, and may lower EA severity measured by PAED scale scores, for which the certainty of evidence was very low.

    One sentence from the abstract (conclusions section), word for word. PMID 42584948.
  8. JAMAAdded to PubMed August 12, 2026E1StrongRandomized trial

    Total Intravenous vs Volatile Inhalational Anesthesia for Major Noncardiac Surgery: A Randomized Clinical Trial.

    Among older adults undergoing major noncardiac surgery, TIVA did not improve days alive and at home at 30 days compared with inhalational anesthesia.

    One sentence from the abstract (conclusions and relevance section), word for word. PMID 42584898.