Epitope Health
Not medical advice. Possible anaphylaxis: use epinephrine and call 911.Read the full note

Epitope Health teaches what published research and FDA labels say, and how strong that evidence is. It cannot know your situation, and nothing here is a diagnosis, a dose for one person, or a decision about whether a food, medicine or procedure suits one person. Those decisions belong with a licensed clinician who can examine you.

If a reaction is happening now, use epinephrine if it has been prescribed and call 911. After surgery, trouble breathing or chest pain needs 911. If you are thinking about harming yourself, call or text 988, any time.

A first aid kit, a stethoscope and blister packs of tablets on a blue surface

Worried about a severe reaction?

Anaphylaxis and epinephrine, hives, alpha-gal, and reactions during anesthesia.

4 guides, about 14 minutes in all

Read this first

Anaphylaxis and epinephrine

Why every guideline puts epinephrine first, what studies of fatal reactions teach, why antihistamines are not a substitute, and what each FDA-approved epinephrine device's label says.

Then, in this order

  1. Hives, mast cells and MCAS

    What hives are, why an antihistamine label says it does not prevent them, and what experts say about mast cell activation syndrome.

    2 min read5 sourcesFor clinicians

  2. Alpha-gal syndrome

    Why reactions to beef, pork or lamb can come hours after a meal, the role of ticks, and the mammal products beyond meat that can be involved.

    2 min read3 sourcesFor clinicians

  3. Allergic reactions during anesthesia

    How often anaphylaxis happens during surgery, the usual culprits, and why food allergies and propofol come up.

    2 min read7 sourcesFor clinicians

The allergist visit checklist

What to note, bring and ask, on one printable page.

Other places to start